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Copper Amino Isolate Serum 3.

NIOD Copper Amino Isolate Serum 3
Serums

About this product

A copper amino isolate serum designed to support skin health and anti-aging concerns.

Best for

Type

Formula notes

Fragrance-freeNo drying alcohol

Full ingredients

Guru Score

83%

Approved

9 experts · Strong agreement
9Gurus
7Approved
1Mixed
1Skip
#15 in SerumsSee the ranking →

What the gurus are saying

Its texture is the standout, experts call it the most beautiful copper peptide serum they've tried, with clear evidence of repeat purchases despite the roughly $90 price tag. The copper peptides are the main draw for anyone who is committed to that active in their routine. Reviewers consistently rate it excellent for skin health and anti-aging work.
Synthesized from 9 expert reviews · most recent take August 2026
Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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Approved
"This first one, the NIOD Copper Amino Isolate Serum, is extremely lightweight and breathable. I refuse to remove copper peptides from my weekly routine, I may not use it every day but I use it multiple times a week because I love the way this ingredient has transformed my skin over the last three years of being consistent with it. I have a lot of favorites when it comes to copper peptides and I love this one, though I also really love a couple of others."
All 10 takes from Sincerely Miss Ash
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"This is called Copper Amino Isolate Serum 3 and I've been using this one just as long as The Ordinary. They are basically the same thing, but this is more advanced because of the ingredients. NIOD is more advanced, which is why this brand is more money than The Ordinary. The ingredients that you see in some of the NIOD products you won't see in The Ordinary brand. I do feel like this provides quicker results, at least from my experience with this product. If I were to compare the two together, this one does give better results. I use it all the time, and I actually use this one more than NIOD just because it's quite pricey, so whenever there is a sale I do like to stock up on it, especially because of the price. It is phenomenal and it has a different texture, very thin like water, and it's also dark blue. Once you open it up you have about six months to finish it. It has a really nice texture that spreads across the skin. It's hydrating, it's not sticky or tacky either, and I've never experienced peeling. You can also use this every day, twice a day. So if you want to take your skin to the next level and you love your peptides, try copper peptides."
LUXURY SKINCARE THAT'S ACTUALLY WORTH THE MONEY - MY MOST USED HIGH-END PRODUCTS WITH REAL RESULTS
"This is truly a holy grail, and copper peptides is one of my favorite ingredients to incorporate on an everyday basis or several times through the week. I love copper peptides because peptides are great, I love peptides, but copper peptides truly take your skin to the next level. It firms the skin a little bit quicker, it also helps to stimulate collagen, it has wound healing properties to it, so it helps to speed up that healing process of the skin, just keeping your skin really healthy and radiant looking. I just love the glow that copper peptides gives my skin as well, especially this product. [...] The texture is very thin, like water, it spreads so nicely, a little bit goes a long way, and it never peels, it's never sticky or tacky, it always sits great with other skincare products. This can be used every day, twice a day as well, but I will use this with other types of peptides, I will use this with vitamin C derivatives, not ascorbic acid but derivatives, and I'll also pair this up with hydrating repairing ingredients also."
6 BEST COPPER PEPTIDE SERUMS || STIMULATE COLLAGEN & ACHIEVE FIRMER SKIN - SINCERELY MISS ASH
"This is the NIOD Copper Amino Isolate Serum 3, the 30 mil size. I love these two, so if I'm done with the Ordinary, I move on to the NIOD, and when I finish this I move back to the Ordinary. I like to alternate between these two the most, but I really do like this option, especially if I'm looking for something that is a little bit more moisturizing, that has that balmy effect. I really like the way that this applies to the skin also."
DECIEM SALE 2024 | MUST HAVE PRODUCTS YOU NEED FROM THE ORDINARY, NIOD & LOOPHA - SINCERELY MISS ASH
"This is a product that I talk a lot about here on my channel and this is a product that I really believe in. You would not believe the results that I have seen with this serum alone, and I have been very consistent with this for over two years now pretty much, and I am just absolutely in love and obsessed with this. Copper peptides have wound healing properties, it can help to stimulate new collagen, address fine lines and wrinkles, and it can help to firm the skin, and I have noticed that with this serum in particular it does help to firm the skin and it does give a glow to the skin as well. Copper peptides has anti-inflammatory properties as well, so if you have facial redness this can help to reduce that rosiness, and it really does. This is a product that can be used every day, twice a day. You do need to be cautious on what you pair this up with, exfoliating acids, with certain types of antioxidants like ascorbic acid, resveratrol, and they also don't recommend using this with retinol, with tretinoin. I have seen a lot of different dermatologist videos where they say that you can use copper peptides with tretinoin, with retinol, I have used it a few times, but I much prefer to keep them separate because I'm seeing great results with it."
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"The next copper peptide that I really love is by NIOD, which is the sister company to The Ordinary. This is the Copper Amino Isolate Serum, and it's very, very similar to the Ordinary one, but this one is a little bit more advanced in terms of the ingredients, and the texture of this is more like water. This one spreads even better across the skin and your skin also absorbs this really nicely. I will say that the Ordinary one is a little bit more moisturizing on the skin because it has that thicker texture, but this one is still quite nice and it really helps to hydrate the skin at the same time. [...] This one comes in two sizes, a 15ml and a 30ml."
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"They are offering 50% off the Copper Amino Isolate Serum, and this is a serum that I talk about a lot on my channel. I use this one almost every day. If I'm not using the Ordinary's copper peptides, I am using this one. I do feel like this one is a little bit more effective, I do feel like this one works a little quicker. This one has more of that watery texture, whereas the one from the Ordinary is more like that jelly, more like a hyaluronic acid type of texture, but they're both amazing. I really, really love this, and it's 50% off, so I'm going to purchase the 30 ml size, and I am going to purchase multiple bottles because why not at 50% off, and I'm going to stock up because it's something I use all the time. It's great for fine lines, great for signs of aging, and I'm telling you, for 50% off, just pick up one and you'll know what I mean."
BEAUTY EMPTIES 2025 || SKINCARE, MAKEUP AND HAIRCARE PRODUCT'S I'VE USED UP - PROJECT PAN
"This is the NIOD Copper Amino Isolate Serum. The ingredients in here are more advanced, and I do find that this works a lot quicker. It's very comparable and similar to the ordinary one, you honestly can't go wrong with either one. This one unfortunately is more expensive, and this one has more of that thin, watery consistency, whereas the other is a little bit more of that gel type of serum that kind of mimics hyaluronic acid in texture. It just depends on what consistency you like better and what your budget is, but these two are exceptional, especially if you're looking for a copper peptide. Yes, I have backups of this, yes I definitely do."
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"It's been a while since I've used this and I can't remember how I liked it. I can't remember if it pilled, how it layered out with my skin care, so I will keep you updated on this in time."
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"I also really love the NIOD copper amino isolate serum. I tend to go back and forth between this and the Ordinary one. I just started using this one last year and I really like it because I feel like it has other ingredients that the Ordinary one does not have, and I find it to be a little bit more advanced than that one. But at the end of the day, you can't go wrong with either one, it just depends on what you prefer to go with and what you're looking for in terms of ingredients, and of course what your budget is as well."
7 BEST LIGHTWEIGHT SKINCARE FOR SUMMER ☀️ | Non-Greasy Products That Layer Perfectly Under Makeup
"This first one, the NIOD Copper Amino Isolate Serum, is extremely lightweight and breathable. I refuse to remove copper peptides from my weekly routine, I may not use it every day but I use it multiple times a week because I love the way this ingredient has transformed my skin over the last three years of being consistent with it. I have a lot of favorites when it comes to copper peptides and I love this one, though I also really love a couple of others."
Approved
"This is the Niod Copper Amino Isolate Serum, which is 93 bucks. The main difference between this and the Ordinary copper peptide serum is the texture. This one's got a very water-like texture, so it's pretty easy to fit into most routines, whereas the Ordinary has kind of a gel serumy texture. It's got 1% copper peptides, tripeptide 29, which they say helps with collagen production, vitamin E, and retinol peptide 189, which is claimed to function similar to retinol."
Top Pick: luxury copper peptide serum
All 3 takes from No BS Beauty
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"Last but not least is the NIOD Copper Amino Isolate Serum 3, which is 47 bucks. This is a copper peptide serum, great for nighttime use to help with anti-aging. We've got 1% copper peptides, we've got vitamin E, we've got that retinol peptide 189, and then we've got proline peptide. It's just a water-based peptide serum, and [...] this one's really nice. [...] In addition to those ingredients, we have an ingredient called tholin 4, which is a peptide that's claimed to work with the youth hormone called thotin. It works by compensating for the loss of thymic factors that come with age, and it's thought to stimulate the skin's immune defenses and help the skin regenerate and produce more collagen, which is what we all want. So buy this for the copper peptides and the other peptides in here, and keep using it for the other beneficial goodies in here. It's really a nice serum."
Favorite LUX Anti Aging Products - Day 7
"This is the Niod Copper Amino Isolate Serum, which is 93 bucks. The main difference between this and the Ordinary copper peptide serum is the texture. This one's got a very water-like texture, so it's pretty easy to fit into most routines, whereas the Ordinary has kind of a gel serumy texture. It's got 1% copper peptides, tripeptide 29, which they say helps with collagen production, vitamin E, and retinol peptide 189, which is claimed to function similar to retinol."
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"Next up would be my luxe pick or more pricey pick. So if you like a little bit more expensive ones, this is a good one. It's the NIOD Copper Amino Isolate Serum. This size retails for 93 bucks, so it is on the more expensive side. It's got 1% copper peptides, and in addition to that, it's got tripeptide-29, which the manufacturers say helps with collagen production, vitamin E, it's got the retinopeptide 189, which is a peptide that claims to have results similar to retinol, increasing skin cell turnover and promoting the synthesis of collagen, and then we've also got the thymulin-4 peptide thought to help stimulate the skin's immune defenses and help the skin regenerate. Really nice watery based serum, easy to fit in with any routine, but definitely on the more expensive price point."
Approved
"One of the most respected products in this space is the NIOD Copper Amino Isolate Serum 3. It's around $65 and is formulated with a 1% copper peptide complex that can help improve skin elasticity and structural anti-aging. It's a great product. [...] A quick practical note, don't layer copper peptides with ascorbic acid, vitamin C. So if you use a vitamin C in the morning, go with your peptides at night."
Approved
"First and foremost, we have the NIOD Copper Amino Isolate Serum. This has been a staple in my routine for years. [...] I think this was one of the first peptide serums I ever used and I've absolutely loved it. It's not the cheapest product out there, but it's definitely an advanced formula that makes sure those peptides get to where they need to be in the skin in order to deliver maximum benefit. Such a great product, such a great formula, and definitely for people that have used peptides for some time and want to kind of kick it up a notch, this is a product that will definitely help you to achieve that. NIOD actually have a 23% off sale which ends at the end of April, so I've just stocked up on this one cause I love it, and that really does bring that price point down. [...] This is an advanced product that definitely takes your peptide game to the next level."
All 8 takes from Mad About Skin
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"If you want to go for the most advanced copper peptide option, then you could reach for the NIOD Copper Amino Isolate Serum 3. This is a fantastic, fantastic product that has multiple layers of technology to make sure those copper peptides are getting to where they need to be to give you quick and effective results. It's also got a great blend of peptides in here which are really going to double down on that collagen production. This is amazing. And because it's part of that ordinary family, they currently have a 23% off sale on this product, which will bring that price point down a little bit. Full price, it is actually a little bit out of the reach of a lot of people, but with that sale on, it will make it slightly more accessible. I think the main reason that people don't opt for copper peptides like the one by NIOD is they find them too complicated. There are lots of things you can't layer and pair alongside them because they can damage the copper peptides, meaning ultimately you're wasting your money."
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"First and foremost, we have the NIOD Copper Amino Isolate Serum. This has been a staple in my routine for years. [...] I think this was one of the first peptide serums I ever used and I've absolutely loved it. It's not the cheapest product out there, but it's definitely an advanced formula that makes sure those peptides get to where they need to be in the skin in order to deliver maximum benefit. Such a great product, such a great formula, and definitely for people that have used peptides for some time and want to kind of kick it up a notch, this is a product that will definitely help you to achieve that. NIOD actually have a 23% off sale which ends at the end of April, so I've just stocked up on this one cause I love it, and that really does bring that price point down. [...] This is an advanced product that definitely takes your peptide game to the next level."
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"When it comes to the best advanced peptide, if you want a product that does it all super quick and gives you the maximum results, I would recommend going for the NIOD Copper Amino Isolate Serum. [...] This is one of my favorite copper peptide serums. The reason this is so advanced is not only does it have a great blend of peptides and copper peptides within it, it also uses a bespoke and patented delivery technology which means that it directs those peptides to where they need to be to get maximum results. So you're getting the key ingredients, but you're also harnessing technology to make sure that it works as quickly and effectively as possible. Take it from me, if you use this serum you will definitely start to notice results in terms of increase in elasticity in the skin, hydration, and plumpness within like a couple of days to a week. In the long term you definitely see that payoff for minimizing fine lines and wrinkles. This is honestly [...] one of the best peptide serums on the market. It's not the cheapest, so shop now if you're wanting to try it out."
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"The standout performer of today is the Copper Amino Isolate Serum by NIOD, the copper peptide I'm using today. There are others on the market, but hands down it's the best copper peptide on skincare planet Earth. It's normally about eighty pounds here in the UK. The technology far outstrips anything else on the market. I do love this, but I will only buy it when it's on sale, I'm too cheap to buy it full price."
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"If you prefer something that isn't in a lipid base but is more traditional serum, then the Copper Amino Isolate Serum is a great option, very similar in terms of outcomes, but this is a little bit more lightweight and has a slightly lower price point. [...] It'll depend what you're looking for, but if you're on a slightly lower budget, don't feel you have to compromise, this is a really great anti-aging option."
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"You only need to use a tiny amount and it spreads beautifully on the skin, so that makes the application super easy. [...] The NIOD Copper Amino Isolate Serum 3 has the same great copper peptide blend as the lipid version, but it's in a more watery serum base. I think this is really going to come down to preference in terms of what you like in terms of texture. [...] If you want something that sinks in super quick, then the serum might be more for you. I tend to mix and match between the two depending on what my skin needs. In summer I will go for the serum, which is more lightweight, in winter I'll go for the more heavy duty lipid, really just matching it with what your skin needs on the day. [...] I think why these are so special is not only do you have that high dose of copper peptides, but you also have the delivery mechanism built in to make sure every single one of those peptides gets to exactly where it needs to be, which is why you get such quick results with both of these products."
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"I just love a lot of copper peptides. Actually, in my routine, I think the best of the best in copper peptides is this NIOD Copper Amino Isolate Serum 3. It's got technology in here that makes sure those copper peptides get to where they need to be in order to deliver maximum results. It's also beautifully hydrating. However, it comes with a higher price point, so whilst this is absolutely worth every penny, for those of you that are on a budget and maybe don't want to stretch to this price point, I hear you."
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"It also actually uses some now trademarked technology. They actually spent so much money on this technology, they went through the trademark process, which is kind of a sign that it's good, to get those peptides to where they need to be in the skin to give you maximum results. So I feel with the Neostrata product you're getting a good dose of peptides, but that technology really helps them work extra hard for you. I find it's a nice middle ground, it's not the cheapest product out there but it's also not super expensive, so it's a good mid price point, and one that I definitely love. The copper peptides in here are the ones that stand out, and whilst it doesn't have quite the same advanced blend of different firming peptides as the first two, it uses that technology to really get maximum results for the skin. So it's a really nice option, worthy a place in this video for sure."
Approved
"If you want the high-end version, the NIOD Copper Amino Isolate Serum 3. That'll cost you about 90 bucks, but it is great overall for skin health."
Skip
"This is NIOD's copper amino isolate serum, and I didn't feel like it did that much for me. I really like peptide ingredients and copper peptide is supposed to be an incredible one, but when I looked into the data there isn't much research on copper peptides. My biggest issue though is how runny it is, it's incredibly unpleasant to use, nearly unusable, and it's still not inexpensive. So that's a no for me."
Mixed
"The NIOD Copper Amino Isolate Serum 3 is fine, it works well, [...] but I don't enjoy using it as much. I find it a bit more unwieldy texturally speaking, [...] it feels like you're putting more on than just a very thin liquid that slips through your fingers. That's really just a personal preference, it doesn't necessarily speak to efficacy per se. [...] Having really given the NIOD one a rigorous test, I found it to be effective, beneficial, but I honestly don't really have a strong reason to encourage you all to buy the NIOD one."
Approved
"The last in the serum category is again repeated from the years before: NIOD Copper Amino Isolate Serum 3, hands down the copper peptide serum with the best texture I have tried."
Top Pick: copper peptide serum
All 3 takes from Doctor Anne
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"The last in the serum category is again repeated from the years before: NIOD Copper Amino Isolate Serum 3, hands down the copper peptide serum with the best texture I have tried."
So many skincare empties - Everything I used up in 2024 | Doctor Anne
"The NIOD Copper Amino Isolate Serum 3 is one I have repurchased numerous times. Yes, it is very expensive, but I want copper peptides in my routine and the texture in this one is the most beautiful I have found, which is why I keep reaching for it."
So many skincare empties - Everything I used up in 2023 | Doctor Anne
"Already repurchased was the NIOD Copper Amino Isolate Serum 3, even more expensive than the Estee Lauder one, but by far the best copper peptides serum I have tried in terms of texture. The first one was PR, the two others I have used since I have purchased myself, that is how much I love it."
Approved
"There's a collagen stimulating peptide, it signals to our body to create collagen, but it also is a carrier peptide for copper and it helps deliver the copper deeper into the skin where it can create more meaningful results, so I really like the combination here, there's some other peptides in the mix. This is a very expensive serum, it's up in the like the $90 range, it's very expensive, it works, it works. This is one of the very few expensive products where I would say if it fits your budget, go for it. I don't think that you will regret it, it will show you results. It made my skin feel so firm so fast, amazing."
All 2 takes from Kelly Driscoll
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"There's a collagen stimulating peptide, it signals to our body to create collagen, but it also is a carrier peptide for copper and it helps deliver the copper deeper into the skin where it can create more meaningful results, so I really like the combination here, there's some other peptides in the mix. This is a very expensive serum, it's up in the like the $90 range, it's very expensive, it works, it works. This is one of the very few expensive products where I would say if it fits your budget, go for it. I don't think that you will regret it, it will show you results. It made my skin feel so firm so fast, amazing."
Skincare That Actually Firms Skin!
"It is an expensive product, I have to admit. It's about $62 for 15ml or $92 for a 30ml bottle, it's pricey. The reason I bring it up though is because it works. I would never recommend something, especially at that price point, if I didn't have personal results with it. This firms the skin, it makes the skin feel [...] thicker but in a good way, thicker and firmer and more lifted. That's how it made my skin feel after a couple of weeks of consistent use. It absolutely firms the skin and it has this really interesting refining quality to the skin. If you have enlarged pores it really helps to smooth those and make them look more refined and slightly tighter. It makes your skin look really smooth, really lifted, it feels thick, it feels firm, and that comes down to those peptides that are helping with the structural integrity of the skin. One of the things when it comes to loose and sagging pores is helping to improve the structural integrity of the skin with all those good proteins, because that's what helps keep the pore from sagging, so that's why we're seeing those results with the pores with this type of serum, [...] but it's also overall helping the skin to feel more firm and lifted. Now, $63 or $92 is just not going to fit your skincare budget, I totally understand, I've been there."
Common questions

Frequently asked.

What is NIOD Copper Amino Isolate Serum 3?

A copper amino isolate serum designed to support skin health and anti-aging concerns.

Is NIOD Copper Amino Isolate Serum 3 worth it?

Mostly yes. 7 of the 9 gurus who reviewed it give it their stamp of approval, for a Guru Score of 83%.

What is NIOD Copper Amino Isolate Serum 3's Guru Score?

NIOD Copper Amino Isolate Serum 3 holds a Guru Score of 83%. That is our read on how warmly the experts talk about it, based on the verdicts of 9 expert reviewers we have collected. At least one expert has named it a Top Pick in its category.

Who is NIOD Copper Amino Isolate Serum 3 best for?

NIOD Copper Amino Isolate Serum 3 is generally suited to mature skin.

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